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The reviewer GM declared a shared affiliation, with no collaboration, with the authors to the handling editor at the time of the review

Current evidence confirms that probiotics, prebiotics, and synbiotics can reshape the structure of gut microbiota and enhance neuroprotection, demonstrating potential to alleviate gastroparesis and improve motility in animal models and limited clinical trials

The critical difference between a drug on the 503B list and an FDA-approved medication is the level of scrutiny, he continued

The rapid evolution of obesity therapeutics coincides with a broader global health crisis

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