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Weight regain after GLP-1 discontinuation is substantial: a post-STEP-1 extension study showed that 68% of weight loss was regained within one year of stopping semaglutide [11]
The mean baseline body weight was 108 kg, and mean BMI was 37 kg/m2
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While natural GLP1 levels fluctuate throughout the day, Ozempic provides a consistent therapeutic effect
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