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A significant decrease in sperm quality was found in Nrf2 knockout mice [93]

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No controlled trial has measured its skin effects or established a reliable results timeline

Another critical study called the PANDA study used 105 sibling pairs to demonstrate that there were no statistically significant differences in intelligence quotient (IQ) scores in later childhood between children who used to receive single anesthesia exposure under 36 months old and siblings with no anesthesia exposure (Sun et al., 2016)

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