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Although NNT is a useful tool to translate treatment efficacy into clinical practice, its derivation requires care
Adipose vs Other NNMT Research Contexts While adipose is the most-developed NNMT-inhibition research application, NNMT biology has been studied in other contexts too: 5-Amino-1MQ as a tool compound has utility across these contexts, but adipose research is currently the deepest and most-established application area
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Although it can be used to mix peptides, it lacks the antimicrobial properties of Bacteriostatic Water, and its salt content may potentially influence peptide stability and effectiveness
Despite initially promising results, SAR425899 has been discontinued after phase 2 trials showed treatment related gastrointestinal disorders (NCT03437720)
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