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Previously approved diabetes drugs were weight neutral or caused weight gain, a concern because obesity is often a co-morbidity of T2DM and can increase the risk for a cardiovascular complication, such as a heart attack or stroke

Acarbose, 17-alpha-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

Precipitates or breaks down during the shelf life of the vial, which could affect dose

According to the model, a population of 100,000 people on tirzepatide had over 46,000 fewer cases of obesity and 32,000 fewer cases of diabetes than a population treated with only a lifestyle management program

Hallym University Hangang Sacred Heart Hospital (Seoul), Inje University Ilsan Paik Hospital (Goyang), Seoul Metropolitan Government Seoul National University Boramae Medical Center (Seoul), Ajou University Medical Center (Suwon), Jeonbuk National University Hospital (Jeonju)