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In addition, qRT-PCR analysis of blood-derived RNA demonstrated a reduction in the mRNA expression levels of connexin 43 (Cx43) and tumor necrosis factor-alpha (TNF-) in both paracetamol-treated (groups A1A3) and ibuprofen-treated (groups B1B4) mice compared with the control group

Chen, J., Chen, G

However, this pathway is reported to be inactive in most tissues, and in the few tissues in which it is active, its function is reduced in tumours from the corresponding tissue 16

The answer is nuanced: L-glutathione and reduced glutathione (GSH) describe the same compound, but the context in which they are used can differ

Neuroinflammation 191 VincentA.BriggsL.ChatwinG