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Claire Davies, Stuart Pape, Suzanne Bassett and Ryan Thurber outline the key timing and potential implications of the July 2324 meeting: To view or add a comment, sign in Tomorrow, the FDA makes one of its biggest moves yet on peptides
Not because it cures everything, but because it can help with almost everything
Synthetic BPC-157 is chemically defined to a single sequence (GEPPPGKPADDAGLV, 1419.5 Da), whereas the native protein is studied as part of a heterogeneous gastric proteome (Sikiric et al., 2018
BPC-157 work centres on local angiogenic signalling, with Hsieh and colleagues (J Mol Med, 2017) reporting VEGFR2 upregulation and internalisation in human endothelial cells, and Chang and colleagues (J Appl Physiol, 2011) reporting increased focal adhesion kinase and paxillin phosphorylation in cultured rat tendon fibroblasts
Use standard PPE: gloves, lab coat, eye protection
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