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10.2174/092986707779313345 Curr Med Chem
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We show here that the Michael acceptor methylene quinuclidinone (MQ), the active form of APR-246, is a potent direct inhibitor of Trx1 and Grx1 by reacting with sulfhydryl groups in the enzymes
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This is a good thing because its soothing and antioxidant activity is a surface-level job anyway
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438 Voltage-gated calcium channels (VGCCs) are functionally diverse and involved in peripheral and central nociception
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While it can be beneficial for many, its not necessarily suitable for everyone
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