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10.1093/CVR/CVZ323 23 HuangM.WeiR.WangY.SuT.LiQ.YangX.et al (2017)
Human islet histology Human islets were incubated overnight in medium plus 11 mM glucose 100 nM agonist prior to transfer to 4 C to arrest endocytosis and labeling with 1 M exendin-FITC, PFA fixation, 70% ethanol dehydration and suspension in 4% agarose small plugs
A phase 2 trial studied exenatide usage on intracranial pressure (ICP) in patients with IIH over 12 weeks
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In addition, the model appears to display a pro-inflammatory state that is relevant to the human metabolic syndrome
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