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Association between SOD deficiency and a number of pathologies has been observed in both animals and humans (Fig
J Ethnopharmacology
The relative abundance of Erysipelatoclostridium was increased in vehicle-treated mice that underwent the WD to LD switch (WD/LD-V) relative to the two control groups (LD/LD-V and WD/WD-V) but was not increased in 5A-1MQ-treated mice that underwent the same diet switch (WD/LD-T)
Loss of Lean Muscle Mass: If muscle mass decreases, so does the resting metabolic rate (RMR) , making it harder to continue burning calories
As a positive control for apoptosis, tamoxifen (50 M) was included ( 2 , 1.2 mM EGTA, 1.5% Nonidet P40, 0.3% CHAPS, 30% sucrose, 150 M caspase 3 substrate DEVD-AMC, 30 mM DTT, and 3.0 mM PMSF was directly added to HepG2 cells
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