The increased numbers of CD21 low B cells implicated in autoimmunity (164167) were also reported in Kabuki syndrome type 1, Rubinstein-Taybi syndromes type 1 and type 2 ( Figure 6G ) (60, 77, 83, 115, 126128) which in some cases were accompanied by autoimmune diseases (83, 115, 126128)
Microscopic examination of mouse colonic tissue reveals reduced inflammatory cell infiltration, maintained crypt morphology, and fewer surface defects in the PYY group compared to controls (Supplementary Fig
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