Anighoro A, Bajorath J, Rastelli G
A total of twenty-five (n=25) male Sprague Dawley rats were used in the Study, with 22 rats allocated for dosing in groups of 2-3 rats randomly assigned per formulated test article examined, and 3 additional animals designated as nave (i.e., untreated) control
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Clinical and basic studies have revealed dysbiosis of the gut microbiota in subjects with neurodegenerative diseases 89,90,91