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Genes involved in tissue repair, collagen synthesis, and antioxidant protection see increased activity, while genes associated with inflammation, tissue breakdown, and cellular aging see reduced expression

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

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Cerovecki T et al

The qRT-PCR primer sets for cDNA amplification were as follows: TNF- (forward: 5-TCCAGGCGGTGCCTATGT-3/reverse: 5-CACCCCGAAGTTCAGTAGACAGA-3), IL-6 (forward: 5-CTGCAAGAGACTTCCATCCAGTT-3/reverse: 5-AAGTAGGG AAGGCCGTGGTT-3), IFN- (forward: 5-TCAAGTGGCATAGATGTGGAAGAA-3/reverse: 5-TGGCTCTGCAGGATTTTCATG-3), CXCL2 (forward: 5-CTCAGTGC TGCACTGGTCCTG-3/reverse: 5-CTGGGGGCGTCACACTCAAG C-3), and GAPDH (forward: 5-CCTCGTCCCGTAGACAAAATG-3/reverse: 5-TCTCCACTTT GCCACTGCAA-3)