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Because of the complex statistical design (drug, genotype, time) and potent effect of both the drug and genotype, sometimes there was no interaction with time (main effect of drug and/or genotype)
Two databases were queried: PubMed and the Web of Science Core Collection (WoSCC)
Mechanisms that commonly induce ROS generation in viral infections include the deregulation of mitochondrial function, activation and upregulation of NOX production, and modification of the Nrf2/ARE pathway, with superoxide being the most commonly produced ROS 55
AOD9604 Phase IIb obesity trial results and program termination announcement
Given the consistent selection of aKG and creatine across all the analytical approaches, their associations with demographic and clinical variables were further explored (Supplemental Tables S4 & S5)
