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Hunger creeps back in, not to pre-treatment levels, but enough that portions start growing, snacks reappear, and calorie-dense convenience foods show up more often

It dials up the activity of genes associated with tissue repair and antioxidant production while turning down those linked to inflammation

23 in placebo MACE-5 (a broader 5-component composite): hazard ratio 0.82 (95% CI 0.551.22) Neither result is statistically significant