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Overproduction of ROS and impaired antioxidant defenses can lead to oxidative stress, which may promote an inflammatory response
Modern large-scale trials aren't available
One publication also suggested that the potential metabolic benefits of berberine could make it a valuable supplement for women who are in the midst of the perimenopausal and postmenopausal transition
For patients who experience a paradoxical decrease in energy levels, it doesnt mean you should stop taking the B12 but instead decrease your dose by half (so take 2,500mcg every 7 days) or simply take 5,000mcg every 14 days instead
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