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The intake of diet and drinking consumed per day was measured for each cage (3 mice per cage) during a following period: each diet treatment for a week, DSS treatment for 3 days or 5 days after each diet treatment for a week

Anti diabetes drugs can affect bone metabolism, for example, TZDs are selective agonists of PPAR - family nuclear receptors

FIGURE 5 The process of scar formation probably exerts a role in protecting the integrity of the blood brain barrier (BBB) and in avoiding further cellular degeneration