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An earlier 12-week trial in 300 obese adults produced a genuine positive signal the 1 mg daily dosing arm showed a statistically significant 2.8 kg mean weight loss versus 0.8 kg in the placebo group and that result is what justified moving into the larger Phase IIb trial

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They found a relative increase of some bacteria like Escherichia, Shigella and Prevotella , which exhibited the higher correlations to IL-8 levels in the hepatic vein

Electrolyte Boost : Try adding electrolyte-rich drinks like coconut water or electrolyte tablets to your water if your symptoms persist, especially if youre experiencing frequent episodes

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