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In fact, all that caffeine can actually cause: Increased heart rate and blood pressure Anxiety or jitteriness Insomnia Upset stomach Headaches Diarrhea or digestive upset And sugar, if youre sensitive to stimulants, have heart conditions, high blood pressure, or youre pregnantyou might wanna steer clear

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And a mild histamine-like inflammatory response can occur in skin not used to active peptide signalling

While this is indicative of how obesity and its treatment were seen at the time, I believe the sentiment is shifting as our knowledge of obesity improves, and our understanding that obesity is a progressive and relapsing disease worthy of high quality treatments and care grows

Bruising is the most common complaint