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Given the similarities between the brain's and retina's vascular systems, these findings suggest that GLP-1R agonism could also protect the brain's microvasculature, preserving the integrity of the blood-brain barrier and improving cerebral blood flow
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Induced pluripotent stem cells: opportunities and challenges
These can lead to insulin resistance, hypertension, joint pain, water retention, and potential cardiovascular or cancer risks
Mechanistically, IS induces eryptosis through multiple interconnected pathways: it elevates intracellular Ca 2+ concentrations, triggering membrane phospholipid scrambling and subsequent phosphatidylserine (PS) externalization
