Excessive differentiation of preadipocytes into mature adipocytes increases adipocyte number and size, ultimately leading to obesity
Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake effects were metabolic, not appetite-driven
Signs that youre not getting enough B12: Fatigue Weakness Confusion Memory issues Headaches Depression Pale skin Pain and swelling in the mouth or tongue Erectile dysfunction Vitamin B12 Benefits B12 is linked to several important functions in the body, including: Red blood cell formation Your body needs B12 to produce healthy red blood cells
Published studies used different routes, including oral and intravenous administration, so the amounts cannot be directly transferred between routes
At excess doses, this pathway could theoretically increase circulating free fatty acids, but no published human trial has reported clinically significant dyslipidemia from acute AOD-9604 overexposure