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Over the past several years, researchers have begun to notice something else
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The vast majority of compounds show a reduced or even complete loss of the therapeutic effect under hypoxic conditions
As a result, K16 and K17 are generally considered as biomarkers and potential therapeutic targets for psoriasis
For testing the difference in mean and median lifespan between groups, we used linear mixed model with linear quantile mixed-effects model, which included cage assignment as a random effect and batch as a covariate, respectively, using package nlme and lgmm in statistical software R
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