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LC-Q-TOF/MS (Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry): Used for peptide sequence confirmation and identification of low-abundance impurities

Papamargaritis D, le Roux CW, Sioka E, Koukoulis G, Tzovaras G, Zacharoulis D

However, the molecular mechanisms underlying this function are not clear

GLP-1 was identified in the early 1980s, and its insulinotropic and anorectic properties were rapidly established

Structural modifications, such as attaching a lipid chain to a lysine residue, can enhance the peptides effectiveness by prolonging its half-life and bioavailability through non-covalent interactions with albumin