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YAP can support compensatory hypertrophy by promoting aerobic glycolysis in pressure overload (15)
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And it plays a role in buffering the mitochondrial acyl-CoA pool, helping maintain metabolic flexibility, the ability to switch between fat and carbohydrate as fuel sources depending on demand
& Brenner, C
It remains to know whether the levels of IGF-IR and IGF-IR have different impact on the prognosis
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