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PubMed laboratory research record [PMID: 800386] PubMed record related to this compound for laboratory literature review
Hope this helps somewhat
A recent systematic review and meta-analysis of 21 randomized, placebo-controlled trials examining the effect of B-vitamin supplementation found the supplementation decreased homocysteine concentrations and improved measures global cognitive function but had no effect on individual measures of executive function, information processing speed, or episodic memory (89)
The 0.25 mg dose can be used as a cautious restart or practice-based taper floor, but it is not tested long-term maintenance
The study design did not have a placebo arm and in a condition such as fibromyalgia, where placebo effects are high, it is difficult to draw any firm conclusions from the results, Professor Littlejohn told Rheumatology Republic
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