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Reduced glutathione is the active form that neutralizes free radicals, while oxidized glutathione occurs when GSH loses an electron after combating oxidative stress

However, the medication's gastrointestinal effectsparticularly nausea, vomiting, and diarrheacan lead to dehydration and prerenal acute kidney injury if fluid intake is inadequate

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This is why combining both peptides is particularly relevant : each addresses a different dimension of the same problem