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As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively
The GFB selectively permits passage of nanoparticles with hydrodynamic diameters 6 months) biodistribution studies for most kidney-targeted nanotherapies, making comprehensive risk assessment challenging
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e421 Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, et al
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