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Importantly, the 2024 systematic review by Sikiric et al

The widespread pharmacotherapy of otherwise healthy populations with overweight or obesity with the goal of improving future health requires further regulatory and ethical consideration

When you add vitamin C to this process, you are providing the liver with the raw materials it needs to keep that "cleansing" cycle moving

The formation of antigenantibody complexes activates the complement system, leading to massive hepatocyte death, suggesting that HBV-ALF may be an HBV core-driven B cell disease[19]

The fairest one-line summary is that DSIP appears to have real biological activity but a weak and inconsistent clinical efficacy signal