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Generally, nausea should improve after a few weeks once your body has had a chance to adjust to the medication or the higher dose, Cardel says

Nettelbladt, C

Duran E, Pandinelli M, Logothetis NK, Eschenko O (2023) Altered norepinephrine transmission after spatial learning impairs sleep-mediated memory consolidation in rats

Do you have a personal or family history of multiple endocrine neoplasia (MEN)

If taking insulin or sulfonylureas for diabetes, the dose of those medications may need to be lowered when starting Zepbound to reduce the risk of hypoglycemia (low blood sugar)