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Other studies have found links between high TMAO levels and heart failure and chronic kidney disease. The authors concluded that the best results from L-carnitine supplementation seem to come from longer term use of at least three months, because of the ingredients low bioavailability
however, its essential to consider the long-term costs
It depends on your goals and lab results
What we can say is that the mechanistic logic is solid, the Phase 2 human data is genuinely impressive, and the glucagon receptor component does appear to add something real beyond what dual agonism achieves
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