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390 PLA 2 also converts PIP2 to DAG and IP3, like PLC, to activate PKC, 450 regulating superoxide production and cytoskeletal rearrangement
10.1016/0162-0134(86)80060-5 J
In September 2025, Lilly quietly terminated one of its two Phase 2 trials for strategic business reasons. 9,10 Scholar Rock (Apitegromab): A selective myostatin inhibitor that only blocks latent myostatin activation, potentially offering a cleaner mechanism
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