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For diabetes management, measurable reductions in hemoglobin A1c typically appear within 4-8 weeks, with maximum effects at 12-16 weeks

LOOH also participates in regulating oxidative stress-related signaling pathways, influencing apoptosis and antioxidant defense mechanisms [93], underscoring its critical role in cardiovascular diseases such as atherosclerosis and in neurodegenerative diseases, triggering tissue damage and pathological progression [93]

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But I do think in layperson conversation, thats still very much part of the conversation