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ACMSD catalyzes the decarboxylation of aminocarboxymuconate-semialdehyde (ACMS) into aminomuconic semialdehyde, which can then enter the citric acid cycle as acetyl-CoA, contributing to cellular respiration

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whereas the increase in estrogen was shown to increase the expression of the anti-apoptotic gene (B-cell lymphoma 2) in mice with cerebral ischemia (Dubal et al., Complete smoking cessation is difficult to achieve during pregnancy, especially in certain communities where maternal smoking rates are particularly high (Chertok and Archer, 2016)