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Taste changes and food aversions, particularly toward fatty or sweet foods, may last 48 weeks but often become less bothersome as patients adjust their food choices

37 DRUG INTERACTIONS Previous trials investigating potential drug interactions with SC semaglutide have yielded few notable interactions, most likely due to the nonspecific mechanisms of metabolism seen with semaglutide

If after eight weeks at progressively increasing microdoses you see no changes in appetite or weight, discuss with your provider whether standard dosing might be more appropriate for your physiology

While speculative, early research suggests microbiome composition influences metabolic health outcomes independently and may be modifiable to improve treatment response