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One in five women, or 20%, reported having ever used GLP-1 agonists. Further, many GLP-1 users report side effects like nausea and diarrhea, the survey found

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Packaging, labeling, regulatory structure-function positioning, and logistics coordination can be aligned to match brand strategy and target market expectations

Funding This work was funded by a Motor Neurone Disease Association grant awarded to RJM (SITraN/Jul16/987-797) and by a tenure track Lectureship awarded to RJM by the Motor Neurone Disease Association funding (SITraN/Apr13/983-797) and the family of Kenneth A Snowman

Additionally, GLP-1 RAs exhibit neuroprotective and anti-inflammatory effects, increase Akt dephosphorylation, decrease proinflammatory factors such as TNF-, elevate neurotrophic factors like BDNF, reduce oxidative stress and microglial activation, and enhance gut-brain axis function and gut microbiota stability [176]