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That 20% reduction in MACE is a landmark finding

Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state

A critical in-license with an unresolved change-of-control clause should trigger an escrow of consideration allocated to that licensed technology until licensor consent is confirmed or the license is renegotiated

Moiz A, Zolotarova T, Filion KB, Eisenberg MJ (2025) GLP-1 Receptor Agonists and Blood Pressure: A State-of-the-Art Review of Mechanisms, Evidence, and Clinical Implications

There are several GLP-1 medications on the market today, each with slightly different strengths