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Acute glucose fluctuation impacts microglial activity, leading to inflammatory activation or self-degradation

The significant increases of 24 h mean heart rate were seen in both groups

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533 Additionally, in a rat model of obesity-related SAP, serum-derived Exos were found to stimulate the secretion of proinflammatory cytokines, including IL-1, IL-6, and TNF-, and exacerbate pancreatitis severity by promoting M1 polarization of adipose tissue macrophages