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In this review, the term redox bottleneck is used as a conceptual framework describing conditions in which oxidative throughput approaches the regenerative capacity of substrate-supported NAD/NADPH-dependent buffering systems under sustained energy flux constriction
Copper binding to the prion protein: structural implications of four identical cooperative binding sites
10.1016/j.bcmd.2016.07.001 Blood Cells Mol Dis
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