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doi: 10.1111/J.1365-2567.2006.02417.X 82 YangLLHuangMSHuangCCWangTHLinMCWuCCet al

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IRE1/XBP1 signaling in tumor growth, angiogenesis, and chemoresistance In parallel to PERK, the IRE1/XBP1 branch of the UPR plays a critical role in sustaining tumor growth and mediating resistance to therapy