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PPs are a large heterogeneous group of secondary plant metabolites, display a wide range of biological activities, and are substantially studied for their anticancer activities (2224)
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The industry is also highly concentrated, giving them significant negotiating leverage
In cultured fibroblasts, GHK-Cu increases synthesis of collagen I and III and of glycosaminoglycans, and modulates the balance of matrix metalloproteinases against their tissue inhibitors (TIMP-1, TIMP-2)
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