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A similar phenomenon has been observed at the calcitonin receptor, another class B1 GPCR, where human calcitonin, with a fast off-rate, turns over G protein faster than salmon calcitonin, which has a slow off-rate, and this was related to differences in the residency time of the G protein on the receptor and to the sensitivity of the G protein to GTP 35
Esta observacin sugiere que la inhibicin de GLP-1 sobre la secrecin de glucagn involucra otro mecanismo adems de la accin inhibicin paracrina de la insulina sobre el glucagn (28,29)
Bailey, J
Verify current COA Independent Janoshik analytical report, surfaced immediately above Panda research-use compliance notice
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