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Among the proposed mechanisms for these effects, the reduction of toxic metabolites from fatty acids, especially LCAC under ischemic conditions, increased glucose oxidation during reperfusion, and consequently the reduction of lactate and H+ ion accumulation, resulting in the inhibition of acidosis in myocardial cells during ischemia, as well as the inhibition of harmful effects of free radicals released during reperfusion, are more prominently noted
doi: 10.1128/mBio.03171-19 13 Cervantes-SilvaM
W., and Yang, Y
Pigmented spots can darken as overall tone rises
Nojiri, S
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