Healthcare providers should discuss this likelihood during shared decision-making conversations, along with considerations of cost, insurance coverage, medication availability, and perioperative management (as these agents delay gastric emptying)
Zepbound (tirzepatide) Approved uses: People with overweight or obesity and moderate-to-severe obstructive sleep apnea Drug type: Once-weekly injection Doses: 2.5 mg (initial dose), 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg Cost: With commercial insurance that includes Zepbound coverage, the cost of a three-month prescription is as low as $25
Anxiety about whether the new medication will work, frustration during retitration periods when appetite returns, and the cognitive load of tracking two different dosing protocols all take a psychological toll
In evoke/evoke+, not all biomarkers are expected to show robust changes in response to treatment, and alterations in A are not expected since semaglutide is not an A-directed agent
For now, however, its still premature to administer prophylactic GLP-1 RAs to patients being treated with lithium. If the GLP-1 RAs can indeed be shown to be nephroprotective, it would affect the risk-benefit evaluation, where currently, many patients dont want to take lithium and many prescribers dont want to prescribe it, so many people who could potentially benefit could now consider it as a viable treatment option, Dr McIntyre said