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Finally, validating the prognostic value of eryptosis in prospective cohortsbuilding on preliminary findings linking eryptosis to cardiovascular risk and peritoneal inflammation severitywill be critical to establishing its clinical relevance beyond anemia management, potentially positioning eryptosis as a broader marker of uremic toxicity and systemic inflammation in CKD

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Most patients begin noticing abdominal changes around the 2-week mark, particularly a shift in how the midsection feels

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In the case of ECs, these models are sometimes also referred to as endothelium-on-a-chip, vessel-on-a-chip, or microvasculature-on-a-chip and sometimes require co-culturing ECs with vascular smooth muscle cells, fibroblasts, and other cells [265, 266]