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What to Expect During and After Your B12 Injection During the injection: Vitamin B12 injections are typically administered by a practice nurse at your GP surgery

After your injection, we may ask you to remain in the clinic for a few minutes, especially if this is your first B12 shot, to monitor for any immediate reactions

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Similarly reduction in methylation cycling due to inactive B12, or lack of folate also leads to reduced myelination

Patients receiving long-term therapy with omeprazole or other proton pump inhibitors (PPIs) should be monitored for signs of B12deficiency