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In another study, IGFBP-3 was able to enhance etoposide-induced cell growth inhibition by blocking the NF-B signaling pathway in gastric cancer cells, confirming that IGFBP-3 has become a key target and marker for cancer therapy and further exploration of its in-depth regulatory mechanisms is worthwhile (91)

These experiments suggest a half-life longer than two days

Both the megadose amount and the long term maintenance dose (up to 20g/day) seems unnecessarily high to me

One outlier, however, is the potential for different immunological reactions individuals allergic to beef may tolerate horse-derived proteins better, though this remains a niche advantage