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Although these preclinical findings are promising for muscle quality, they need to be confirmed in clinical studies, as human data remain scarce

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Enzymes such as Dipeptidyl Peptidase-4 (DPP-4) and Neutral Endopeptidase (NEP) contribute to this process, yielding inactive biological fragments (23)(30) Semaglutide, Serum, and tissue proteases metabolize the polypeptide into amino acids, clearing it from the system and preventing accumulation (23)(21)