If you are curious about what those first weeks feel like, the initial experience on semaglutide varies considerably from person to person, though most people notice appetite suppression within the first one to two weeks
Meglutide participates in the activity of the appetite regulation center
10.1001/jamainternmed.2024.4369 Summary Keywords cardiovascular disease, cardiovascular outcome, glucagon-like peptide-1 receptor agonists, heart failure, obesity Citation Turkistani Y (2025) Glucagon-like peptide-1 receptor agonists: a review from a cardiovascular perspective
GLP-1 receptor agonists mimic a hormone in your body that: Regulates appetite and reduces hunger
has received speaker/consultancy fees from Boehringer Ingelheim, Janssen, Karuna, Lundbeck, Otsuka and Viatris, and co-directs a company that designs digital resources to support treatment of mental ill health