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Even in non-diabetic patients with chronic kidney disease, semaglutide reduces albuminuria by 52.1%, indicating significant renal protection ^43

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There is also a separate safety question, distinct from efficacy: retatrutide raises resting heart rate by 5 to 10 beats per minute, which has not yet been characterised in patients who already have heart failure or irregular heartbeats

Originators (like Novo Nordisk and Eli Lilly) hold patents that prevent competition

Scott Fears, chief medical officer at Amae Health, told Behavioral Health Business