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No significant heterogeneity among studies ( I 2 = 50%, p =0.06), so the fixed-effects model was used to combine the effect sizes

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Mol Pharmacol 83:191205 Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M (2003) cAMP promotes pancreatic -cell survival via CREB-mediated induction of IRS2

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